Reaction Details  Report a problem with these data
Cell Reactant:
Cyclin-dependent kinase 2
Syringe Reactant:
BDBM225324
Meas. Tech.:
Enzyme Inhibition
Entry Date.:
05/10/17
ΔG°:
-9.67±0.93 (kcal/mole)
Temperature:
298±0 (K)
ΔH° :
-4.31±0.65 (kJ/mole)
ΔS° :
0.02±0 (kJ/mole-K)
Citation
 D3R, DD CSAR CDK2-CyclinA D3R 219:0 (2015) [PubMed] 
Cell React
Name:
Cyclin-dependent kinase 2
Synonyms:
CDK2 | CDK2-Kinase | CDK2_HUMAN | CDKN2 | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | Protein cereblon/Cyclin-dependent kinase 2 | p33 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
33938.17
Organism:
Homo sapiens (Human)
Description:
P24941
Residue:
298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
  
Syringe React
Name:
BDBM225324
Synonyms:
CS261
Type:
Small Organic Molecule
Emp. Form.:
C20H19N7O4S
Mol. Mass.:
453.474
SMILES:
NS(=O)(=O)c1ccc(N\N=C2/C(=O)Nc3ccc(cc23)C(=O)NCCc2c[nH]cn2)cc1
Structure:
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