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Target
POU domain, class 5, transcription factor 1
Ligand
BDBM306793
Substrate
n/a
Meas. Tech.
OCT3 inhibitory activity
IC50
8200±n/a nM
Citation
 Yamashita, H; Suzuki, N OCT3 activity inhibitor containing imidazopyridine derivative as active component, and OCT3 detection agent US Patent  US10149840 Publication Date 12/11/2018 
Target
Name:
POU domain, class 5, transcription factor 1
Synonyms:
Octamer-binding protein 3 | Oct-3 | Octamer-binding protein 4 | Oct-4 | Octamer-binding transcription factor 3 | OTF-3 | PO5F1_HUMAN | POU5F1 | OCT3 | OCT4 | OTF3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38567.64
Organism:
Human
Description:
Q01860
Residue:
360
Sequence:
MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN
  
Inhibitor
Name:
BDBM306793
Synonyms:
US10149840, Compound SR-4277 | US10149840, Series Number 12
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CC1=CC2=NC(CN2C=C1)C(=O)NCCSCc1ccccc1F |c:9,t:1,3|
Structure:
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