Reaction Details Report a problem with these data
Target
External core antigen
Ligand
BDBM576277
Substrate
n/a
Meas. Tech.
PHH Natural Infection Assay
IC50
1940±n/a nM
Citation
 Xianfeng, L; Hongying, Y; Bo, Z; Xiufang, Z N-SUBSTITUTED 4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)ANILINE FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION WIPO 0:0 (2022) [PubMed] 
Target
Name:
External core antigen
Synonyms:
C | HBEAG_HBVGB | HBeAg | Precore protein | p25
Type:
Protein
Mol. Mass.:
24103.68
Organism:
HBVgbn
Description:
P89951
Residue:
212
Sequence:
MQLFHLCLIISCSCPTVQASKLCLGWLLGMDIDPYKEFGASVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPNHTALRQAVLCWGELMTGCSWVGNNLEDPASRELVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSPASQC
  
Inhibitor
Name:
BDBM576277
Synonyms:
WO2022112139, Example 15
Type:
Small organic molecule
Emp. Form.:
C22H15F2N3O3
Mol. Mass.:
407.3696
SMILES:
FC(F)Oc1ccccc1C(=O)Nc1ccc(cc1)-c1nnc(o1)-c1ccccc1
Structure:
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