Reaction Details Report a problem with these data
Target
External core antigen
Ligand
BDBM576354
Substrate
n/a
Meas. Tech.
PHH Natural Infection Assay
IC50
594±n/a nM
Citation
 Hongying, Y; Bo, Z; Xiufang, Z AROMATIC BRIDGED RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION WIPO 0:0 (2022) [PubMed] 
Target
Name:
External core antigen
Synonyms:
C | HBEAG_HBVGB | HBeAg | Precore protein | p25
Type:
Protein
Mol. Mass.:
24103.68
Organism:
HBVgbn
Description:
P89951
Residue:
212
Sequence:
MQLFHLCLIISCSCPTVQASKLCLGWLLGMDIDPYKEFGASVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPNHTALRQAVLCWGELMTGCSWVGNNLEDPASRELVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSPASQC
  
Inhibitor
Name:
BDBM576354
Synonyms:
WO2022112205, Example 11
Type:
Small organic molecule
Emp. Form.:
C20H18ClN3O4S
Mol. Mass.:
431.893
SMILES:
Clc1ccc2oc(nc2c1)C12CC(C1)(C2)NC(=O)c1ccc(o1)S(=N)(=O)C1CC1
Structure:
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