Reaction Details Report a problem with these data
Target
External core antigen
Ligand
BDBM576366
Substrate
n/a
Meas. Tech.
PHH Natural Infection Assay
IC50
1871±n/a nM
Citation
 Hongying, Y; Bo, Z; Xiufang, Z AROMATIC BRIDGED RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION WIPO 0:0 (2022) [PubMed] 
Target
Name:
External core antigen
Synonyms:
C | HBEAG_HBVGB | HBeAg | Precore protein | p25
Type:
Protein
Mol. Mass.:
24103.68
Organism:
HBVgbn
Description:
P89951
Residue:
212
Sequence:
MQLFHLCLIISCSCPTVQASKLCLGWLLGMDIDPYKEFGASVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPNHTALRQAVLCWGELMTGCSWVGNNLEDPASRELVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSPASQC
  
Inhibitor
Name:
BDBM576366
Synonyms:
WO2022112205, Example 21
Type:
Small organic molecule
Emp. Form.:
C20H17ClN2O2S
Mol. Mass.:
384.879
SMILES:
CSc1cccc(c1)C(=O)NC12CC(C1)(C2)c1nc2cc(Cl)ccc2o1
Structure:
Search PDB for entries with ligand similarity: