Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM590781
Substrate
n/a
Meas. Tech.
CB1 and CB2 Receptor Binding Assay
IC50
0.700±n/a nM
Citation
 Elzein, E; Liu, J Cannabinoid receptor type 2 (CB2) modulators and uses thereof US Patent  US11564928 Publication Date 1/31/2023 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM590781
Synonyms:
6-(4-methoxyphenyl)-1-(2- morpholinoethyl)-2-oxo-N-(spiro[2.5]octan-6-yl)- 1,2-dihydro-1,8-naphthyridine-3-carboxamide | US11564928, Compound 28
Type:
Small organic molecule
Emp. Form.:
C30H36N4O4
Mol. Mass.:
516.6312
SMILES:
COc1ccc(cc1)-c1cnc2n(CCN3CCOCC3)c(=O)c(cc2c1)C(=O)NC1CCC2(CC2)CC1
Structure:
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