Reaction Details Report a problem with these data
Target
Surfeit locus protein 1
Ligand
BDBM50012956
Substrate
n/a
Meas. Tech.
Binding Activity of the Compounds of the Present Disclosure for SUR1 Receptor
IC50
230±n/a nM
Citation
 HUANG, J; ZHU, L; YU, X; SUN, P SULFONYLUREA DERIVATIVE AND MEDICAL USES THEREOF US Patent  US20230348371 Publication Date 11/2/2023 
Target
Name:
Surfeit locus protein 1
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
33342.60
Organism:
Human
Description:
Q15526
Residue:
300
Sequence:
MAAVAALQLGLRAAGLGRAPASAAWRSVLRVSPRPGVAWRPSRCGSSAAEASATKAEDDSFLQWVLLLIPVTAFGLGTWQVQRRKWKLNLIAELESRVLAEPVPLPADPMELKNLEYRPVKVRGCFDHSKELYMMPRTMVDPVREAREGGLISSSTQSGAYVVTPFHCTDLGVTILVNRGFVPRKKVNPETRQKGQIEGEVDLIGMVRLTETRQPFVPENNPERNHWHYRDLEAMARITGAEPIFIDANFQSTVPGGPIGGQTRVTLRNEHLQYIVTWYGLSAATSYLWFKKFLRGTPGV
  
Inhibitor
Name:
BDBM50012956
Synonyms:
Glucotrol xl | Glucotrol | CHEMBL1073 | K-4024 | 1-cyclohexyl-3-[[p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl]sulfonyl]urea | 1-cyclohexyl-3-(4-(2-(2-methylpyrazine-5-carboxamido)ethyl)phenylsulfonyl)urea | CP-28720 | GLIPIZIDE | US20230348371, Compound Glipizide
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
Cc1cnc(cn1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1
Structure:
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