Reaction Details Report a problem with these data
Target
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
Ligand
BDBM690795
Substrate
n/a
Meas. Tech.
Inhibition Activity
Kd
>10000±n/a nM
Citation
 Gray, NS; Teng, M; Wang, E; Jiang, J; Zhang, T; Cantley, LC; Fischer, ES; Donovan, KA INHIBITORS AND DEGRADERS OF PIP4K PROTEIN US Patent  US20240277852 Publication Date 8/22/2024 
Target
Name:
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta
Synonyms:
PI42B_HUMAN | PIP4K2B | PIP5K2B | Phosphatidylinositol-5-phosphate 4-kinase type-2 beta
Type:
PROTEIN
Mol. Mass.:
47382.97
Organism:
Human
Description:
ChEMBL_774395
Residue:
416
Sequence:
MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNILT
  
Inhibitor
Name:
BDBM690795
Synonyms:
US20240277852, Compound 1
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
Cc1cc(ccc1Nc1ncc(Cl)c(n1)-c1cccc(c1)-c1ccccc1)S(N)(=O)=O
Structure:
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