Reaction Details Report a problem with these data
Target
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
Ligand
BDBM690795
Substrate
n/a
Meas. Tech.
Inhibition Activity
IC50
>10000±n/a nM
Citation
 Gray, NS; Teng, M; Wang, E; Jiang, J; Zhang, T; Cantley, LC; Fischer, ES; Donovan, KA INHIBITORS AND DEGRADERS OF PIP4K PROTEIN US Patent  US20240277852 Publication Date 8/22/2024 
Target
Name:
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
Synonyms:
1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha | 2.7.1.149 | Diphosphoinositide kinase 2-alpha | PI(5)P 4-kinase type II alpha | PIP4KII-alpha | PIP5KIII | Phosphatidylinositol 5-phosphate 4-kinase type II alpha | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | PtdIns(4)P-5-kinase B isoform | PtdIns(4)P-5-kinase C isoform | PtdIns(5)P-4-kinase isoform 2-alpha | PI42A_HUMAN | PIP4K2A | PI5P4KA | PIP5K2 | PIP5K2A | Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha
Type:
PROTEIN
Mol. Mass.:
46228.59
Organism:
Human
Description:
ChEMBL_104274
Residue:
406
Sequence:
MATPGNLGSSVLASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT
  
Inhibitor
Name:
BDBM690795
Synonyms:
US20240277852, Compound 1
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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