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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM15583
Substrate
BDBM10990
Meas. Tech.
MAO Activity Assay
pH
7.4000±n/a
Temperature
311.1500±n/a K
Ki
250±n/a nM
Citation
 La Regina, G; Silvestri, R; Artico, M; Lavecchia, A; Novellino, E; Befani, O; Turini, P; Agostinelli, E New pyrrole inhibitors of monoamine oxidase: synthesis, biological evaluation, and structural determinants of MAO-A and MAO-B selectivity. J Med Chem 50:922-31 (2007) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
Amine oxidase [flavin-containing] A | MAO-A | Monoamine oxidase type A | Monoamine oxidase A | AOFA_BOVIN | MAOA | Monoamine oxidase | Monoamine Oxidase Type A (MAO-A)
Type:
PROTEIN
Mol. Mass.:
59764.63
Organism:
Bovine
Description:
ChEMBL_1501477
Residue:
527
Sequence:
MESLQKTSDAGQMFDVVVIGGGISGLSAAKLLAEHEVNVLVLEARERVGGRTYTVRNEHVDYVDVGGAYVGPTQNRILRLSKQLGLETYKVNVNERLVHYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTMDNMGKEIPADAPWEAPHAVEWDKMTMKDLIEKICWTKTARQFASLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSITNGGQERKFVGGSGQVSERIMQLLGDRVKLRSPVTYVDQSSENITVETLNRELYECRYVISAIPPTLTAKIHFRPELPSERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEEAPISITLDDTKPDGSLPAIMGFILARKADRLAKVHKDIRKRKICELYAKVLGSQEALHPVHYEEKNWCQEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKLSAKDIWIQEPEAEDVPAVEITPSFWERNLPSVSGLLKIVGFSTSITALWFVMYRFRLLSRS
  
Inhibitor
Name:
BDBM15583
Synonyms:
CHEMBL174040 | N-Benzyl-1H-pyrrole-2-carboxamide | pyrrole inhibitor 9
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
BDBM10990
Synonyms:
Diaminopropiophenone | 3-amino-1-(2-aminophenyl)propan-1-one | Kynuramine
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: