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Target
Granulocyte-macrophage colony-stimulating factor
Ligand
BDBM65497
Substrate
n/a
Meas. Tech.
cytomteric bead array (CBA) assay
Temperature
310.15±n/a K
IC50
2.20±n/a nM
Comments
extracted
Citation
 Gandhi, A; Dimartino, J; Chopra, R Methods for the treatment of locally advanced breast cancer US Patent  US9694015 Publication Date 7/4/2017 
Target
Name:
Granulocyte-macrophage colony-stimulating factor
Synonyms:
CSF | CSF2 | CSF2_HUMAN | Colony-stimulating factor | GM-CSF | GMCSF | Molgramostin | Sargramostim
Type:
Protein
Mol. Mass.:
16291.07
Organism:
Homo sapiens (Human)
Description:
P04141
Residue:
144
Sequence:
MWLQSLLLLGTVACSISAPARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVISEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWEPVQE
  
Inhibitor
Name:
BDBM65497
Synonyms:
CC-220 (Compound 6) | US9694015, 6.4S
Type:
Small organic molecule
Emp. Form.:
C25H27N3O5
Mol. Mass.:
449.499
SMILES:
O=C1N(Cc2c1cccc2OCc1ccc(CN2CCOCC2)cc1)[C@H]1CCC(=O)NC1=O
Structure:
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