Reaction Details Report a problem with these data
Target
Carbonic anhydrase 15 [19-324]
Ligand
BDBM26989
Substrate
BDBM10856
Meas. Tech.
CA Inhibition Assay
Ki
61200±n/a nM
Citation
 Innocenti, A; Hilvo, M; Parkkila, S; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors: the membrane-associated isoform XV is highly inhibited by inorganic anions. Bioorg Med Chem Lett 19:1155-8 (2009) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 15 [19-324]
Synonyms:
CA-XV | CAH15_MOUSE | Ca15 | Car15 | Carbonate dehydratase XV | Carbonic Anhydrase XV
Type:
Enzyme
Mol. Mass.:
33409.51
Organism:
Mus musculus (mouse)
Description:
Mouse cloned isozyme.
Residue:
306
Sequence:
VDSSGTWCYDSQDPKCGPAHWKELAPACGGPTQSPINIDLRLVQRDYTLKPFIFQGYDSAPQDPWVLENDGHTVLLRVNSCQQNCPAIRGAGLPSPEYRLLQLHFHWGSPGHQGSEHSLDEKHGSMEMHMVHMNTKYQSMEDARSQPDGFAILAVLLVEEDRDNTNFSAIVSGLKNLSSPGVAVNLTSTFALASLLPSALRLLRYYRYSGSLTTPGCEPAVLWTVFENTVPIGHAQVVQFQAVLQTGPPGLHPRPLTSNFRPQQPLGGRRISASPEASVRSSVSTLPCLHLALVGLGVGLRLWQGP
  
Inhibitor
Name:
BDBM26989
Synonyms:
CHEMBL93268 | NO2- | nitrite | nitrite ion
Type:
Ion
Emp. Form.:
NO2
Mol. Mass.:
46.006
SMILES:
[O-]N=O
Structure:
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Substrate
Name:
BDBM10856
Synonyms:
Carbon Dioxide | methanedione
Type:
Small organic molecule
Emp. Form.:
CO2
Mol. Mass.:
44.0095
SMILES:
O=C=O
Structure:
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