Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM29091
Substrate
BDBM21244
Meas. Tech.
CB Receptor Radioligand Binding Assay (Ki)
Ki
1630±n/a nM
Citation
 Appendino, G; Ligresti, A; Minassi, A; Cascio, MG; Allarà, M; Taglialatela-Scafati, O; Pertwee, RG; De Petrocellis, L; Di Marzo, V Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes. J Med Chem 52:3001-9 (2009) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CANNABINOID CB2 | CB-2 | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Human
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM29091
Synonyms:
cyclopropanolamide, 14b
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
BDBM21244
Synonyms:
CP-56667 [(+)-AC],XV | CP-55,940 | 2-[(1S,2S,5S)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]-5-(2-methyloctan-2-yl)phenol | 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol | CP 55,940 | [3H]-56 | [3H]CP55940
Type:
radiolabeled ligand
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: