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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM15613
Substrate
BDBM29135
Meas. Tech.
MAO Enzyme Inhibition Assay
Citation
 Chimenti, F; Fioravanti, R; Bolasco, A; Chimenti, P; Secci, D; Rossi, F; Yáñez, M; Orallo, F; Ortuso, F; Alcaro, S Chalcones: a valid scaffold for monoamine oxidases inhibitors. J Med Chem 52:2818-24 (2009) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
MAO-B | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) | AOFB_HUMAN | MAOB
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Human
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM15613
Synonyms:
MCL | Aurorix | 4-chloro-N-[2-(morpholin-4-yl)ethyl]benzamide | CHEMBL86304 | 4-chloro-N-(2-morpholin-4-ylethyl)benzamide | Moclobemide
Type:
Small organic molecule
Emp. Form.:
C13H17ClN2O2
Mol. Mass.:
268.10
SMILES:
Clc1ccc(cc1)C(=O)NCCN1CCOCC1
Structure:
Search PDB for entries with ligand similarity:
Substrate
Name:
BDBM29135
Synonyms:
CHEMBL11608 | cid_5610 | tyramine | p-Tyramine
Type:
Small organic molecule
Emp. Form.:
C8H11NO
Mol. Mass.:
137.08
SMILES:
c1cc(ccc1CCN)O
Structure:
Search PDB for entries with ligand similarity: