Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM37330
Substrate
n/a
Meas. Tech.
S1P3 Agonist Dose-Response Potency Assay
EC50
222000±n/a nM
Citation
 PubChem, PC S1P3 Agonist Dose-Response Potency Assay PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
S1PR3_HUMAN | S1PR3 | C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Human
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM37330
Synonyms:
cid_2084313 | 2-[[5,7-bis(chloranyl)-2-methyl-quinolin-8-yl]oxymethyl]-5-(2-bromophenyl)-1,3,4-oxadiazole | 2-(2-bromophenyl)-5-[(5,7-dichloro-2-methyl-8-quinolinyl)oxymethyl]-1,3,4-oxadiazole | 2-(2-bromophenyl)-5-[(5,7-dichloro-2-methylquinolin-8-yl)oxymethyl]-1,3,4-oxadiazole | MLS000058391 | SMR000064058 | 2-(2-bromophenyl)-5-[(5,7-dichloro-2-methyl-8-quinolyl)oxymethyl]-1,3,4-oxadiazole
Type:
Small organic molecule
Emp. Form.:
C19H12BrCl2N3O2
Mol. Mass.:
462.95
SMILES:
Cc1ccc2c(Cl)cc(Cl)c(OCc3nnc(o3)-c3ccccc3Br)c2n1
Structure:
Search PDB for entries with ligand similarity: