Target
fMet-Leu-Phe receptor
Ligand
BDBM37707
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
IC50
>66700±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37707
Synonyms:
(2Z)-2-amino-3-({(1E)-[4-(diethylamino)phenyl]methylene}amino)but-2-enedinitrile | (Z)-2-amino-3-[[4-(diethylamino)benzylidene]amino]but-2-enedinitrile | (Z)-2-amino-3-[[4-(diethylamino)phenyl]methylideneamino]-2-butenedinitrile | (Z)-2-amino-3-[[4-(diethylamino)phenyl]methylideneamino]but-2-enedinitrile | (Z)-2-azanyl-3-[[4-(diethylamino)phenyl]methylideneamino]but-2-enedinitrile | MLS000087650 | SMR000023871 | cid_3238678
Type:
Small organic molecule
Emp. Form.:
C15H17N5
Mol. Mass.:
267.329
SMILES:
CCN(CC)c1ccc(C=NC(C#N)C(=N)C#N)cc1 |w:10.10|
Structure:
Search PDB for entries with ligand similarity: