Reaction Details Report a problem with these data
Target
fMet-Leu-Phe receptor
Ligand
BDBM37820
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
IC50
27400±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Homo sapiens (Human)
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37820
Synonyms:
5-methyl-7-oxidanylidene-6-(phenylmethyl)-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile | 5-methyl-7-oxo-6-(phenylmethyl)-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile | 6-Benzyl-5-methyl-7-oxo-4,7-dihydro-pyrazolo[1,5-a]pyrimidine-3-carbonitrile | 6-benzyl-5-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile | 6-benzyl-7-keto-5-methyl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile | MLS000123585 | SMR000124167 | cid_754780
Type:
Small organic molecule
Emp. Form.:
C15H12N4O
Mol. Mass.:
264.282
SMILES:
Cc1nc2c(c[nH]n2c(=O)c1Cc1ccccc1)C#N
Structure:
Search PDB for entries with ligand similarity: