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Target
Neuropeptide Y receptor type 2
Ligand
BDBM36851
Substrate
n/a
Meas. Tech.
Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism
IC50
7737±n/a nM
Citation
 PubChem, PC Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM36851
Synonyms:
MLS000072751 | N-(5-Benzotriazol-1-ylmethyl-[1,3,4]thiadiazol-2-yl)-4-tert-butyl-N-ethyl-benzamide | N-[5-(1-benzotriazolylmethyl)-1,3,4-thiadiazol-2-yl]-4-tert-butyl-N-ethylbenzamide | N-[5-(benzotriazol-1-ylmethyl)-1,3,4-thiadiazol-2-yl]-4-tert-butyl-N-ethyl-benzamide | N-[5-(benzotriazol-1-ylmethyl)-1,3,4-thiadiazol-2-yl]-4-tert-butyl-N-ethylbenzamide | SMR000004710 | cid_649706
Type:
Small organic molecule
Emp. Form.:
C22H24N6OS
Mol. Mass.:
420.531
SMILES:
CCN(C(=O)c1ccc(cc1)C(C)(C)C)c1nnc(Cn2nnc3ccccc23)s1
Structure:
Search PDB for entries with ligand similarity: