Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM42421
Substrate
n/a
Meas. Tech.
Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism
IC50
30590±n/a nM
Citation
 PubChem, PC Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM42421
Synonyms:
2-[[[2-(4-chlorophenyl)-5-methyl-3-pyrazolyl]amino]methylidene]propanedioic acid diethyl ester | 2-[[[2-(4-chlorophenyl)-5-methyl-pyrazol-3-yl]amino]methylene]malonic acid diethyl ester | MLS000541363 | SMR000126221 | cid_3849628 | diethyl 2-({[1-(4-chlorophenyl)-3-methyl-1H-pyrazol-5-yl]amino}methylene)malonate | diethyl 2-[[[2-(4-chlorophenyl)-5-methyl-pyrazol-3-yl]amino]methylidene]propanedioate | diethyl 2-[[[2-(4-chlorophenyl)-5-methylpyrazol-3-yl]amino]methylidene]propanedioate
Type:
Small organic molecule
Emp. Form.:
C18H20ClN3O4
Mol. Mass.:
377.822
SMILES:
CCOC(=O)C(C=Nc1cc(C)nn1-c1ccc(Cl)cc1)C(=O)OCC |w:7.7|
Structure:
Search PDB for entries with ligand similarity: