Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 2
Ligand
BDBM42424
Substrate
n/a
Meas. Tech.
Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism
IC50
>35000±n/a nM
Citation
 PubChem, PC Dose response counterscreen assay for neuropeptide Y receptor Y1 (NPY-Y1): Cell-based high throughput assay to measure NPY-Y2 antagonism PubChem Bioassay (2008)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM42424
Synonyms:
MLS000519740 | N-cyclohexyl-2-[2-furanylmethyl-(1-oxo-2-thiophen-2-ylethyl)amino]-2-methylbutanamide | N-cyclohexyl-2-[2-furfuryl-[2-(2-thienyl)acetyl]amino]-2-methyl-butyramide | N-cyclohexyl-2-[furan-2-ylmethyl(2-thiophen-2-ylethanoyl)amino]-2-methyl-butanamide | N-cyclohexyl-2-[furan-2-ylmethyl-(2-thiophen-2-ylacetyl)amino]-2-methylbutanamide | SMR000130158 | cid_5140222
Type:
Small organic molecule
Emp. Form.:
C22H30N2O3S
Mol. Mass.:
402.55
SMILES:
CCC(C)(N(Cc1ccco1)C(=O)Cc1cccs1)C(=O)NC1CCCCC1
Structure:
Search PDB for entries with ligand similarity: