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Target
Neuropeptide Y receptor type 2
Ligand
BDBM46522
Substrate
n/a
Meas. Tech.
Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.
EC50
>35430±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2. PubChem Bioassay (2009)[AID] 
Target
Name:
Neuropeptide Y receptor type 2
Synonyms:
NPY-Y2 | NPY-Y2 receptor | NPY2-R | NPY2R | NPY2R_HUMAN | Neuropeptide Y receptor type 2 | Y2 receptor | neuropeptide Y receptor Y2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
42734.65
Organism:
Homo sapiens (Human)
Description:
NPY-Y2 NPY2R HUMAN::P49146
Residue:
381
Sequence:
MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV
  
Inhibitor
Name:
BDBM46522
Synonyms:
2-[(Furan-2-ylmethyl)-amino]-succinic acid 1-(2-methoxy-ethyl) ester | 3-(2-furanylmethylamino)-4-(2-methoxyethoxy)-4-oxobutanoic acid | 3-(2-furfurylamino)-4-keto-4-(2-methoxyethoxy)butyric acid | 3-(furan-2-ylmethylamino)-4-(2-methoxyethoxy)-4-oxidanylidene-butanoic acid | 3-(furan-2-ylmethylamino)-4-(2-methoxyethoxy)-4-oxobutanoic acid | MLS000807054 | SMR000414868 | cid_3259549
Type:
Small organic molecule
Emp. Form.:
C12H17NO6
Mol. Mass.:
271.2665
SMILES:
COCCOC(=O)C(CC(O)=O)NCc1ccco1
Structure:
Search PDB for entries with ligand similarity: