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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78627
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
2375±102 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78627
Synonyms:
1-[(Z)-[2-oxidanylidene-1-(3-oxidanylidene-1H-2-benzofuran-1-yl)indol-3-ylidene]amino]thiourea | MLS000551729 | SMR000145654 | [(Z)-(2-keto-1-phthalidyl-indolin-3-ylidene)amino]thiourea | [(Z)-[2-oxo-1-(3-oxo-1H-2-benzofuran-1-yl)indol-3-ylidene]amino]thiourea | [(Z)-[2-oxo-1-(3-oxo-1H-isobenzofuran-1-yl)-3-indolylidene]amino]thiourea | cid_9633698
Type:
Small organic molecule
Emp. Form.:
C17H12N4O3S
Mol. Mass.:
352.367
SMILES:
NC(=S)NN=C1C(=O)N(C2OC(=O)c3ccccc23)c2ccccc12 |w:4.3|
Structure:
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