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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78669
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
509±44 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78669
Synonyms:
1-[(2-keto-5,7-dimethyl-indol-3-yl)amino]-3-(tetrahydrofurfuryl)thiourea | 1-[(5,7-dimethyl-2-oxidanylidene-indol-3-yl)amino]-3-(oxolan-2-ylmethyl)thiourea | 1-[(5,7-dimethyl-2-oxo-3-indolyl)amino]-3-(2-oxolanylmethyl)thiourea | 1-[(5,7-dimethyl-2-oxoindol-3-yl)amino]-3-(oxolan-2-ylmethyl)thiourea | MLS000417314 | SMR000242559 | cid_5992118
Type:
Small organic molecule
Emp. Form.:
C16H20N4O2S
Mol. Mass.:
332.421
SMILES:
Cc1cc(C)c2=NC(=O)C(NNC(=S)NCC3CCCO3)=c2c1 |c:21,t:5|
Structure:
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