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Target
Ubiquitin-conjugating enzyme E2 N
Ligand
BDBM78899
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm
IC50
1524±142 nM
Citation
 PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay (2011)[AID] 
Target
Name:
Ubiquitin-conjugating enzyme E2 N
Synonyms:
BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N
Type:
PROTEIN
Mol. Mass.:
17137.61
Organism:
Homo sapiens (Human)
Description:
EBI_101440
Residue:
152
Sequence:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
  
Inhibitor
Name:
BDBM78899
Synonyms:
1-(2-methoxyethyl)-3-[(5-nitro-2-oxidanylidene-indol-3-yl)amino]thiourea | 1-(2-methoxyethyl)-3-[(5-nitro-2-oxo-3-indolyl)amino]thiourea | 1-(2-methoxyethyl)-3-[(5-nitro-2-oxoindol-3-yl)amino]thiourea | 1-[(2-keto-5-nitro-indol-3-yl)amino]-3-(2-methoxyethyl)thiourea | MLS000759991 | SMR000370042 | cid_6055390
Type:
Small organic molecule
Emp. Form.:
C12H13N5O4S
Mol. Mass.:
323.328
SMILES:
COCCNC(=S)N[NH+]=C1C(=O)[N-]c2ccc(cc12)[N+]([O-])=O |w:8.7|
Structure:
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