Reaction Details Report a problem with these data
Target
X-box-binding protein 1
Ligand
BDBM67994
Substrate
n/a
Meas. Tech.
XBP1 DR counterscreen for CHOP
IC50
170±n/a nM
Citation
 PubChem, PC XBP1 DR counterscreen for CHOP PubChem Bioassay (2011)[AID] 
Target
Name:
X-box-binding protein 1
Synonyms:
TREB5 | XBP1 | XBP1_HUMAN | XBP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
28704.14
Organism:
Homo sapiens (Human)
Description:
gi_47678753
Residue:
261
Sequence:
MVVVAAAPNPADGTPKVLLLSGQPASAAGAPAGQALPLMVPAQRGASPEAASGGLPQARKRQRLTHLSPEEKALRRKLKNRVAAQTARDRKKARMSELEQQVVDLEEENQKLLLENQLLREKTHGLVVENQELRQRLGMDALVAEEEAEAKGNEVRPVAGSAESAALRLRAPLQQVQAQLSPLQNISPWILAVLTLQIQSLISCWAFWTTWTQSCSSNALPQSLPAWRSSQRSTQKDPVPYQPPFLCQWGRHQPSWKPLMN
  
Inhibitor
Name:
BDBM67994
Synonyms:
MLS000573618 | N-[3-(2,2-dimethyl-4-oxanyl)-3-(4-fluorophenyl)propyl]-N-(phenylmethyl)-2-furancarboxamide | N-[3-(2,2-dimethyloxan-4-yl)-3-(4-fluorophenyl)propyl]-N-(phenylmethyl)furan-2-carboxamide | N-benzyl-N-[3-(2,2-dimethyloxan-4-yl)-3-(4-fluorophenyl)propyl]furan-2-carboxamide | N-benzyl-N-[3-(2,2-dimethyltetrahydro-2H-pyran-4-yl)-3-(4-fluorophenyl)propyl]-2-furamide | N-benzyl-N-[3-(2,2-dimethyltetrahydropyran-4-yl)-3-(4-fluorophenyl)propyl]-2-furamide | SMR000195407 | cid_2902133
Type:
Small organic molecule
Emp. Form.:
C28H32FNO3
Mol. Mass.:
449.557
SMILES:
CC1(C)CC(CCO1)C(CCN(Cc1ccccc1)C(=O)c1ccco1)c1ccc(F)cc1
Structure:
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