Reaction Details Report a problem with these data
Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM42069
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
4410±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM42069
Synonyms:
2-acetamido-4,5-dinitro-benzoic acid ethyl ester | 2-acetamido-4,5-dinitrobenzoic acid ethyl ester | MLS000698400 | SMR000224624 | cid_4104905 | ethyl 2-(acetylamino)-4,5-dinitrobenzoate | ethyl 2-acetamido-4,5-dinitro-benzoate | ethyl 2-acetamido-4,5-dinitrobenzoate
Type:
Small organic molecule
Emp. Form.:
C11H11N3O7
Mol. Mass.:
297.2209
SMILES:
CCOC(=O)c1cc(c(cc1NC(C)=O)[N+]([O-])=O)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: