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Target
DNA damage-inducible transcript 3 protein
Ligand
BDBM68151
Substrate
n/a
Meas. Tech.
CHOP dose-response primary assay
IC50
<160±n/a nM
Citation
 PubChem, PC CHOP dose-response primary assay PubChem Bioassay (2011)[AID] 
Target
Name:
DNA damage-inducible transcript 3 protein
Synonyms:
Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:
Enzyme Catalytic Domain
Mol. Mass.:
19175.17
Organism:
Mus musculus
Description:
gi_160707929
Residue:
168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASLAWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMKEKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
  
Inhibitor
Name:
BDBM68151
Synonyms:
4-amino-2-[(E)-3-(3-fluorophenyl)-1-oxoprop-2-enyl]isoindole-1,3-dione | 4-amino-2-[(E)-3-(3-fluorophenyl)acryloyl]isoindoline-1,3-quinone | 4-amino-2-[(E)-3-(3-fluorophenyl)prop-2-enoyl]isoindole-1,3-dione | 4-azanyl-2-[(E)-3-(3-fluorophenyl)prop-2-enoyl]isoindole-1,3-dione | MLS000516706 | SMR000342857 | cid_5990949
Type:
Small organic molecule
Emp. Form.:
C17H11FN2O3
Mol. Mass.:
310.2792
SMILES:
Nc1cccc2C(=O)N(C(=O)\C=C\c3cccc(F)c3)C(=O)c12
Structure:
Search PDB for entries with ligand similarity: