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Target
D(1B) dopamine receptor
Ligand
BDBM60917
Substrate
n/a
Ki
11±n/a nM
Comments
PDSP_816
Citation
 Tiberi, M; Jarvie, KR; Silvia, C; Falardeau, P; Gingrich, JA; Godinot, N; Bertrand, L; Yang-Feng, TL; Fremeau, RT; Caron, MG Cloning, molecular characterization, and chromosomal assignment of a gene encoding a second D1 dopamine receptor subtype: differential expression pattern in rat brain compared with the D1A receptor. Proc Natl Acad Sci U S A 88:7491-5 (1991) [PubMed]  Article 
Target
Name:
D(1B) dopamine receptor
Synonyms:
D(1B) dopamine receptor | Dopamine D5 receptor | DOPAMINE D5 | DRD5_RAT | Drd5 | Dopamine receptor | Dopamine D1B
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52827.88
Organism:
Rat
Description:
Dopamine D1B 0 RAT::P25115
Residue:
475
Sequence:
MLPPGRNRTAQPARLGLQRQLAQVDAPAGSATPLGPAQVVTAGLLTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGTFCDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQLNWHRDKAGSQGQEGLLSNGTPWEEGWELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSRGAYEPDPSLRASIKKETKVFKTLSMIMGVFVCCWLPFFILNCMVPFCSSGDAEGPKTGFPCVSETTFDIFVWFGWANSSLNPIIYAFNADFRKVFAQLLGCSHFCFRTPVQTVNISNELISYNQDTVFHKEIATAYVHMIPNAVSSGDREVGEEEEEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFDKTA
  
Inhibitor
Name:
BDBM60917
Synonyms:
MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid | 9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid | FENOLDOPAM | FENOLDOPAM MESYLATE | SMR000469190 | cid_49659 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid
Type:
Small organic molecule
Emp. Form.:
C16H16ClNO3
Mol. Mass.:
305.08
SMILES:
Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12
Structure:
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