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Target
Alpha-1A adrenergic receptor
Ligand
BDBM31046
Substrate
n/a
Ki
1.27±n/a nM
Comments
PDSP_1479
Citation
 Jones, SB; Smith, JM; Jones, AW; Bylund, DB Alpha-1 adrenergic receptor binding in aortas from rat and dog: comparison of [3H]prazosin and beta-iodo-[125I]-4-hydroxyphenyl-ethyl-aminomethyl-tetralone. J Pharmacol Exp Ther 241:875-81 (1987) [PubMed] 
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
ADA1A_CANLF | ADRA1A | ADRA1C | adrenergic Alpha1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
32268.65
Organism:
Dog
Description:
adrenergic Alpha1 0 Dog::O77621
Residue:
295
Sequence:
MVFLSGNASDSSNCTHPPAPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQITEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPVGGTGVSSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIG
  
Inhibitor
Name:
BDBM31046
Synonyms:
3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid | 3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride | 3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid | 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid | MLS000069487 | PHENTOLAMINE | PHENTOLAMINE MESYLATE | SMR000059054 | cid_5775 | cid_91430
Type:
Small organic molecule
Emp. Form.:
C17H19N3O
Mol. Mass.:
281.3523
SMILES:
Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 |t:10|
Structure:
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