Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM15336
Substrate
n/a
Ki
2500±n/a nM
Comments
PDSP_2710
Citation
 Schwabe, U; Ukena, D; Lohse, MJ Xanthine derivatives as antagonists at A1 and A2 adenosine receptors. Naunyn Schmiedebergs Arch Pharmacol 330:212-21 (1985) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM15336
Synonyms:
1-methyl-3-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione | 1-methyl-3-(2-methylpropyl)-3,7-dihydro-1H-purine-2,6-dione | 3-Isobutyl-1-methylxanthine | CHEMBL275084 | IBMX | isobutylmethylxanthine
Type:
Small organic molecule
Emp. Form.:
C10H14N4O2
Mol. Mass.:
222.2438
SMILES:
CC(C)Cn1c2nc[nH]c2c(=O)n(C)c1=O
Structure:
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