Reaction Details
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Report a problem with these dataTarget
Prostacyclin receptor
Ligand
BDBM50109546
Substrate
n/a
Ki
16.6±n/a nM
Comments
PDSP_1472
Citation
MacDermot, J; Blair, IA; Cresp, TM Prostacyclin receptors of a neuronal hybrid cell line. Divalent citations and ligand-receptor coupling. Biochem Pharmacol 30:2041-4 (1981) [PubMed] Article More Info.:
Target
Name:
Prostacyclin receptor
Synonyms:
PI2R_MOUSE | Prostacyclin receptor | Prostaglandin I | Prostaglandin I2 | Ptgir
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44475.65
Organism:
MOUSE
Description:
Prostaglandin I2 PTGIR MOUSE::P43252
Residue:
415
Sequence:
MMASDGHPGPPSVTPGSPLSAGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGARRRSHPSAFAVLVTGLAVTDLLGTCFLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARFALPSIYAFCCLFCSLPLLGLGEHQQYCPGSWCFIRMRSAQPGGCAFSLAYASLMALLVTSIFFCNGSVTLSLYHMYRQQRRHHGSFVPTSRAREDEVYHLILLALMTVIMAVCSLPLMIRGFTQAIAPDSREMGDLLAFRFNAFNPILDPWVFILFRKAVFQRLKFWLCCLCARSVHGDLQAPLSRPASGRRDPPAPTSLQAKEGSWVPLSSWGTGQVAPLTAVPLTGGDGCSVGMPSKSEAIAACSLC
Inhibitor
Name:
BDBM50109546
Synonyms:
5-[(3aS,4R,5R,6aS)-5-Hydroxy-4-((S)-3-hydroxy-oct-1-enyl)-hexahydro-pentalen-(2Z)-ylidene]-pentanoic acid | 5-[5-Hydroxy-4-(3-hydroxy-oct-1-enyl)-hexahydro-pentalen-2-ylidene]-pentanoic acidCarbacyclin | CARBACYCLIN | CHEMBL148319 | PGI2
Type:
Small organic molecule
Emp. Form.:
C21H34O4
Mol. Mass.:
350.4923
SMILES:
CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2C\C(C[C@H]12)=C\CCCC(O)=O
Structure:
