Reaction Details Report a problem with these data
Target
Gastrin/cholecystokinin type B receptor
Ligand
BDBM50084033
Substrate
n/a
Ki
0.06±n/a nM
Comments
PDSP_2198
Citation
 Ito, H; Sogabe, H; Nakarai, T; Sato, Y; Tomoi, M; Kadowaki, M; Matsuo, M; Tokoro, K; Yoshida, K Pharmacological profile of FK480, a novel cholecystokinin type-A receptor antagonist: comparison to loxiglumide. J Pharmacol Exp Ther 268:571-5 (1994) [PubMed] 
Target
Name:
Gastrin/cholecystokinin type B receptor
Synonyms:
CCKBR | Cholecystokinin A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48683.10
Organism:
GUINEA PIG
Description:
Cholecystokinin A CCKBR GUINEA PIG::H0VZC5
Residue:
450
Sequence:
MELLKLNRSLQGPGPGPGAPLCRPAGPLLNSSGAGNVSCETPRIRGAGTRVKSMAILFNVTSLLSCWNKYRIIKVLGLSRRLRTVTKAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTAVQPVGPRVLQCVHRWPNARVRQTWSVLLLLLLFFVPGVVMAVAYGLISRELYLGLRFDGDADSESQSRVRGPGGLSGSAPGPAHQNGRCRPESGLSGEDSDGCYVQLPRSRPALELSALAASTPAPGPGPRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPEEDPPTPSIASLSRLSYTTISTLGPG
  
Inhibitor
Name:
BDBM50084033
Synonyms:
1H-Indole-2-carboxylic acid [(R)-1-(2-fluoro-phenyl)-4-oxo-3,4,6,7-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-3-yl]-amide | CHEMBL333994 | FK480
Type:
Small organic molecule
Emp. Form.:
C26H19FN4O2
Mol. Mass.:
438.4531
SMILES:
Fc1ccccc1C1=N[C@@H](NC(=O)c2cc3ccccc3[nH]2)C(=O)N2CCc3cccc1c23 |t:8|
Structure:
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