Reaction Details
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5-hydroxytryptamine receptor 7
Ligand
BDBM50024202
Substrate
n/a
Ki
1.12±n/a nM
Comments
PDSP_184
Citation
To, ZP; Bonhaus, DW; Eglen, RM; Jakeman, LB Characterization and distribution of putative 5-ht7 receptors in guinea-pig brain. Br J Pharmacol 115:107-16 (1995) [PubMed] Article More Info.:
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT7 | 5-HT7L | 5HT7R_CAVPO | HTR7 | Serotonin 7 (5-HT7) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49632.36
Organism:
GUINEA PIG
Description:
5-HT7 HTR7 GUINEA PIG::P50407
Residue:
446
Sequence:
MMGVNSSGRPDLYGHLHSILLPGRGLPDWSPDGGADPGVSTWTPRLLSGVPEVAASPSPSWDGTWDNVSGCGEQINYGRAEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVIPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMPKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYRIYKAARKSAAKHKFPGFPRVQPESIISLNGMVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTACSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPECVLQNSDYCRKKGHDS
Inhibitor
Name:
BDBM50024202
Synonyms:
5-HT,omega-N-Me | 5-OH-ME-Nw Tryptamine | CHEMBL277362 | N-methylserotonin
Type:
Small organic molecule
Emp. Form.:
C11H14N2O
Mol. Mass.:
190.2417
SMILES:
CNCCc1c[nH]c2ccc(O)cc12
Structure:
