Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 5B
Ligand
BDBM50010301
Substrate
n/a
Ki
1000±n/a nM
Comments
PDSP_1725
Citation
 Erlander, MG; Lovenberg, TW; Baron, BM; de Lecea, L; Danielson, PE; Racke, M; Slone, AL; Siegel, BW; Foye, PE; Cannon, K Two members of a distinct subfamily of 5-hydroxytryptamine receptors differentially expressed in rat brain. Proc Natl Acad Sci U S A 90:3452-6 (1993) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 5B
Synonyms:
Serotonin 5b (5-HT5b) receptor | 5-hydroxytryptamine receptor 5B | 5HT5B_RAT | Htr5b | 5ht5b | Serotonin (5-HT) receptor | 5-HT5B
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41141.95
Organism:
Rat
Description:
5-HT5B 0 RAT::P35365
Residue:
370
Sequence:
MEVSNLSGATPGIAFPPGPESCSDSPSSGRSMGSTPGGLILSGREPPFSAFTVLVVTLLVLLIAATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVAALVMPLSLVSELSAGRRWQLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHLQYTLRTRRRASALMIAITWALSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFSTCGAFYVPLAVVLFVYWKIYKAAKFRFGRRRRAVVPLPATTQAKEAPQESETVFTARCRATVAFQTSGDSWREQKEKRAAMMVGILIGVFVLCWIPFFLTELVSPLCACSLPPIWKSIFLWLGYSNSFFNPLIYTAFNKNYNNAFKSLFTKQR
  
Inhibitor
Name:
BDBM50010301
Synonyms:
SKF 83566 | CHEMBL324017 | 8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol(SKF 83566)
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CN1CCc2cc(Br)c(O)cc2C(C1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: