Reaction Details
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5-hydroxytryptamine receptor 4
Ligand
BDBM50056401
Substrate
n/a
Ki
7.94±n/a nM
Comments
PDSP_1689
Citation
Grossman, CJ; Kilpatrick, GJ; Bunce, KT Development of a radioligand binding assay for 5-HT4 receptors in guinea-pig and rat brain. Br J Pharmacol 109:618-24 (1993) [PubMed] Article More Info.:
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
5-HT4 | 5-hydroxytryptamine receptor 4 | 5HT4R_CAVPO | HTR4 | Serotonin 4 (5-HT4) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43735.29
Organism:
GUINEA PIG
Description:
5-HT4 HTR4 GUINEA PIG::O70528
Residue:
388
Sequence:
MDKLDANVSSKEGFGSVEKVVLLTFLSAVILMAILGNLLVMVAVCRDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWVYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHARQIQVLQRAGAPAEGRPQPADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQLWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRDTVECGGQWESQCHPAASSPLVAAQPIDT
Inhibitor
Name:
BDBM50056401
Synonyms:
2-diethylaminoethyl [2-methoxy-4-amino-5-chloro]benzoate | 4-Amino-5-chloro-2-methoxy-benzoic acid 2-diethylamino-ethyl ester | CHEMBL287045 | SDZ 205557 | SDZ-205557
Type:
Small organic molecule
Emp. Form.:
C14H21ClN2O3
Mol. Mass.:
300.781
SMILES:
CCN(CC)CCOC(=O)c1cc(Cl)c(N)cc1OC
Structure:
