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Target
Carbonic anhydrase 9
Ligand
BDBM50031588
Substrate
n/a
Meas. Tech.
ChEMBL_1673888 (CHEMBL4023917)
KOFF
0.000013 s-1
Citation
 Linkuvienė, V; Talibov, VO; Danielson, UH; Matulis, D Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design. J Med Chem 61:2292-2302 (2018) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 9
Synonyms:
CA-IX | Carbonic anhydrase IX (CAIX) | Carbonate dehydratase IX | Carbonic anhydrase 9 (CA IX) | Membrane antigen MN | Carbonic anhydrase IX (CA IX) | Carbonic anhydrase 9 precursor | Carbonic anhydrase 9 (CAIX) | RCC-associated antigen G250 | CAH9_HUMAN | CA9 | G250 | MN | Carbonic anhydrases; II & IX | Carbonic anhydrases IX
Type:
Enzyme
Mol. Mass.:
49669.03
Organism:
Human
Description:
Catalytic domain of human cloned isozyme was used in the assay
Residue:
459
Sequence:
MAPLCPSPWLPLLIPAPAPGLTVQLLLSLLLLVPVHPQRLPRMQEDSPLGGGSSGEDDPLGEEDLPSEEDSPREEDPPGEEDLPGEEDLPGEEDLPEVKPKSEEEGSLKLEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRYGGDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPLELLGFQLPPLPELRLRNNGHSVQLTLPPGLEMALGPGREYRALQLHLHWGAAGRPGSEHTVEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLEEGPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSRYFQYEGSLTTPPCAQGVIWTVFNQTVMLSAKQLHTLSDTLWGPGDSRLQLNFRATQPLNGRVIEASFPAGVDSSPRAAEPVQLNSCLAAGDILALVFGLLFAVTSVAFLVQMRRQHRRGTKGGVSYRPAEVAETGA
  
Inhibitor
Name:
BDBM50031588
Synonyms:
CHEMBL3359181
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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