Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50247455
Substrate
n/a
Meas. Tech.
ChEMBL_1677782 (CHEMBL4027925)
IC50
4140±n/a nM
Citation
 Petrelli, R; Scortichini, M; Belardo, C; Boccella, S; Luongo, L; Capone, F; Kachler, S; Vita, P; Del Bello, F; Maione, S; Lavecchia, A; Klotz, KN; Cappellacci, L Structure-Based Design, Synthesis, and In Vivo Antinociceptive Effects of Selective A J Med Chem 61:305-318 (2018) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | Adenosine A3 receptor (A3AR) | AA3R_HUMAN | ADORA3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Human
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50247455
Synonyms:
CHEMBL4098408
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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