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Target
Glucagon receptor
Ligand
BDBM50266693
Substrate
n/a
Meas. Tech.
ChEMBL_1701188 (CHEMBL4052170)
EC50
0.0004±n/a nM
Citation
 Evers, A; Haack, T; Lorenz, M; Bossart, M; Elvert, R; Henkel, B; Stengelin, S; Kurz, M; Glien, M; Dudda, A; Lorenz, K; Kadereit, D; Wagner, M Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists. J Med Chem 60:4293-4303 (2017) [PubMed]  Article 
Target
Name:
Glucagon receptor
Synonyms:
GCGR | GL-R | GLR_HUMAN | Glucagon Receptor (GCGR) | Glucagon receptor (GlucR)
Type:
Enzyme
Mol. Mass.:
54026.92
Organism:
Homo sapiens (Human)
Description:
P47871
Residue:
477
Sequence:
MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
  
Inhibitor
Name:
BDBM50266693
Synonyms:
CHEBI:5391 | Glucagen Hypokit | Glucagon | Glucagon Emergency Kit | Glucagon Recombinant
Type:
Small organic molecule
Emp. Form.:
C153H225N43O49S
Mol. Mass.:
3482.747
SMILES:
n/a
Structure:
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