Reaction Details Report a problem with these data
Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50013536
Substrate
n/a
Meas. Tech.
ChEBML_52212
Ki
18±n/a nM
Citation
 Youssefyeh, RD; Magnien, E; Lee, TD; Chan, WK; Lin, CJ; Galemmo, RA; Johnson, WH; Tan, J; Campbell, HF; Huang, FC Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 1. Initial structure-activity relationships. J Med Chem 33:1186-94 (1990) [PubMed]  Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
Guinea pig
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50013536
Synonyms:
2-{4-[4-(2H-Tetrazol-5-yl)-butyl]-phenoxymethyl}-quinoline | CHEMBL97541 | 2-{4-[4-(1H-Tetrazol-5-yl)-butyl]-phenoxymethyl}-quinoline
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
C(CCc1ccc(OCc2ccc3ccccc3n2)cc1)Cc1nnn[nH]1
Structure:
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