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Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM50454060
Substrate
n/a
Meas. Tech.
ChEMBL_1751788 (CHEMBL4186548)
EC50
2000±n/a nM
Citation
 Kinoshita, A; Higashino, M; Yoshida, K; Aratani, Y; Kakuuchi, A; Hanada, K; Takeda, H; Naganawa, A; Matsuya, H; Ohmoto, K Synthesis and evaluation of a potent, well-balanced EP Bioorg Med Chem 26:200-214 (2018) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
Prostanoid EP1 receptor | Prostaglandin E2 receptor EP1 subtype | PGE receptor, EP1 subtype | PE2R1_HUMAN | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype (EP1)
Type:
Enzyme
Mol. Mass.:
41834.57
Organism:
Human
Description:
P34995
Residue:
402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
  
Inhibitor
Name:
BDBM50454060
Synonyms:
CHEMBL4208379
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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