Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1D
Ligand
BDBM50458555
Substrate
n/a
Meas. Tech.
ChEMBL_1764104 (CHEMBL4199351)
Ki
2112±n/a nM
Citation
 Kim, Y; Kim, H; Lee, J; Lee, JK; Min, SJ; Seong, J; Rhim, H; Tae, J; Lee, HJ; Choo, H Discovery of β-Arrestin Biased Ligands of 5-HT J Med Chem 61:7218-7233 (2018) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1D
Synonyms:
5-hydroxytryptamine receptor 1D (5-HT1D) | 5-HT1D | 5-HT-1D | 5-HT-1D-alpha | Serotonin Receptor 1D | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41920.63
Organism:
Human
Description:
Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:
377
Sequence:
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAKAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS
  
Inhibitor
Name:
BDBM50458555
Synonyms:
CHEMBL4207884
Type:
Small organic molecule
Emp. Form.:
C13H14ClN3
Mol. Mass.:
247.73
SMILES:
Clc1ccc(cc1)-c1n[nH]c2CCNCCc12
Structure:
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