Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 4
Ligand
BDBM50458555
Substrate
n/a
Meas. Tech.
ChEMBL_1764110 (CHEMBL4199357)
Ki
>10000±n/a nM
Citation
 Kim, Y; Kim, H; Lee, J; Lee, JK; Min, SJ; Seong, J; Rhim, H; Tae, J; Lee, HJ; Choo, H Discovery of β-Arrestin Biased Ligands of 5-HT J Med Chem 61:7218-7233 (2018) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 4
Synonyms:
Serotonin Receptor 4 | 5-HT-4 | 5-HT4S | 5-HT4 | Serotonin (5-HT3) receptor | 5-HT4d | 5-hydroxytryptamine receptor 4 | 5-HT4hb | 5-HT4a | Serotonin (5-HT) receptor | Serotonin 4 (5-HT4) receptor | 5-HT4b | 5-HT4c | 5HT4R_HUMAN | HTR4 | 5-hydroxytryptamine receptor 4 (5-HT4)
Type:
Enzyme
Mol. Mass.:
43767.54
Organism:
Human
Description:
Q13639
Residue:
388
Sequence:
MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT
  
Inhibitor
Name:
BDBM50458555
Synonyms:
CHEMBL4207884
Type:
Small organic molecule
Emp. Form.:
C13H14ClN3
Mol. Mass.:
247.73
SMILES:
Clc1ccc(cc1)-c1n[nH]c2CCNCCc12
Structure:
Search PDB for entries with ligand similarity: