Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50458555
Substrate
n/a
Meas. Tech.
ChEMBL_1764102 (CHEMBL4199349)
Ki
>10000±n/a nM
Citation
 Kim, Y; Kim, H; Lee, J; Lee, JK; Min, SJ; Seong, J; Rhim, H; Tae, J; Lee, HJ; Choo, H Discovery of β-Arrestin Biased Ligands of 5-HT J Med Chem 61:7218-7233 (2018) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5HT1A_HUMAN | ADRB2RL1 | ADRBRL1 | G-21 | 5-hydroxytryptamine receptor 1A (5-HT-1A) | 5-HT-1A | 5-HT1A | HTR1A | Serotonin receptor 1A | Dopamine D2 receptor and serotonin 1a receptor
Type:
n/a
Mol. Mass.:
46122.49
Organism:
Human
Description:
n/a
Residue:
422
Sequence:
MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
  
Inhibitor
Name:
BDBM50458555
Synonyms:
CHEMBL4207884
Type:
Small organic molecule
Emp. Form.:
C13H14ClN3
Mol. Mass.:
247.73
SMILES:
Clc1ccc(cc1)-c1n[nH]c2CCNCCc12
Structure:
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