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Target
Envelope glycoprotein
Ligand
BDBM50459313
Substrate
n/a
Meas. Tech.
ChEMBL_1766237 (CHEMBL4201484)
EC50
1020±n/a nM
Citation
 Wang, C; Zhao, L; Xia, S; Zhang, T; Cao, R; Liang, G; Li, Y; Meng, G; Wang, W; Shi, W; Zhong, W; Jiang, S; Liu, K De Novo Design of α-Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-Spectrum Antiviral Drug Discovery. J Med Chem 61:8734-8745 (2018) [PubMed]  Article 
Target
Name:
Envelope glycoprotein
Synonyms:
Envelope glycoprotein | GP1 | GP1,2 | GP1,2-delta | GP2 | Shed GP | VGP_EBOZM | GP
Type:
PROTEIN
Mol. Mass.:
74464.56
Organism:
ZEBOV
Description:
ChEMBL_117434
Residue:
676
Sequence:
MGVTGILQLPRDRFKRTSFFLWVIILFQRTFSIPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKNLTRKIRSEELSFTVVSNGAKNISGQSPARTSSDPGTNTTTEDHKIMASENSSAMVQVHSQGREAAVSHLTTLATISTSPQSLTTKPGPDNSTHNTPVYKLDISEATQVEQHHRRTDNDSTASDTPSATTAAGPPKAENTNTSKSTDFLDPATTTSPQNHSETAGNNNTHHQDTGEESASSGKLGLITNTIAGVAGLITGGRRTRREAIVNAQPKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYIEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPHDWTKNITDKIDQIIHDFVDKTLPDQGDNDNWWTGWRQWIPAGIGVTGVIIAVIALFCICKFVF
  
Inhibitor
Name:
BDBM50459313
Synonyms:
CHEMBL4206744
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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