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Target
D-amino-acid oxidase
Ligand
BDBM31148
Substrate
n/a
Meas. Tech.
ChEMBL_1768986 (CHEMBL4221098)
Kd
150±n/a nM
Citation
 Szilágyi, B; Kovács, P; Ferenczy, GG; Rácz, A; Németh, K; Visy, J; Szabó, P; Ilas, J; Balogh, GT; Monostory, K; Vincze, I; Tábi, T; Szök?, É; Keser?, GM Discovery of isatin and 1H-indazol-3-ol derivatives as d-amino acid oxidase (DAAO) inhibitors. Bioorg Med Chem 26:1579-1587 (2018) [PubMed]  Article 
Target
Name:
D-amino-acid oxidase
Synonyms:
D-Amino Acid Oxidase (DAAO) | D-amino-acid oxidase (DAAO) | DAMOX | DAO | OXDA_PIG
Type:
Flavoprotein
Mol. Mass.:
39338.01
Organism:
Sus scrofa (pig)
Description:
Homodimer.
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDVKVYADRFTPFTTTDVAAGLWQPYTSEPSNPQEANWNQQTFNYLLSHIGSPNAANMGLTPVSGYNLFREAVPDPYWKDMVLGFRKLTPRELDMFPDYRYGWFNTSLILEGRKYLQWLTERLTERGVKFFLRKVESFEEVARGGADVIINCTGVWAGVLQPDPLLQPGRGQIIKVDAPWLKNFIITHDLERGIYNSPYIIPGLQAVTLGGTFQVGNWNEINNIQDHNTIWEGCCRLEPTLKDAKIVGEYTGFRPVRPQVRLEREQLRFGSSNTEVIHNYGHGGYGLTIHWGCALEVAKLFGKVLEERNLLTMPPSHL
  
Inhibitor
Name:
BDBM31148
Synonyms:
3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1
Type:
Small organic molecule
Emp. Form.:
C9H7NO2
Mol. Mass.:
161.1574
SMILES:
Oc1cc2ccccc2[nH]c1=O
Structure:
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