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Target
Protein-lysine 6-oxidase
Ligand
BDBM50463618
Substrate
n/a
Meas. Tech.
ChEMBL_1778827 (CHEMBL4235819)
IC50
1600±n/a nM
Citation
 Hajdú, I; Kardos, J; Major, B; Fabó, G; Lőrincz, Z; Cseh, S; Dormán, G Inhibition of the LOX enzyme family members with old and new ligands. Selectivity analysis revisited. Bioorg Med Chem Lett 28:3113-3118 (2018) [PubMed]  Article 
Target
Name:
Protein-lysine 6-oxidase
Synonyms:
LYOX_HUMAN | LOX | Lysyl oxidase | alpha-Glucosidase (alpha-Glu)
Type:
PROTEIN
Mol. Mass.:
46954.13
Organism:
Human
Description:
ChEMBL_306619
Residue:
417
Sequence:
MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSLGSQYQPQRRRDPGAAVPGAANASAQQPRTPILLIRDNRTAAARTRTAGSSGVTAGRPRPTARHWFQAGYSTSRAREAGASRAENQTAPGEVPALSNLRPPSRVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY
  
Inhibitor
Name:
BDBM50463618
Synonyms:
CHEMBL4241062
Type:
Small organic molecule
Emp. Form.:
C15H15N7O2
Mol. Mass.:
325.33
SMILES:
CC1=NN(C(=O)\C1=C\NNc1nnc(C)c(O)n1)c1ccccc1 |t:1|
Structure:
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