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Target
Protein-lysine 6-oxidase
Ligand
BDBM50463620
Substrate
n/a
Meas. Tech.
ChEMBL_1778827 (CHEMBL4235819)
IC50
9200±n/a nM
Citation
 Hajdú, I; Kardos, J; Major, B; Fabó, G; Lőrincz, Z; Cseh, S; Dormán, G Inhibition of the LOX enzyme family members with old and new ligands. Selectivity analysis revisited. Bioorg Med Chem Lett 28:3113-3118 (2018) [PubMed]  Article 
Target
Name:
Protein-lysine 6-oxidase
Synonyms:
LYOX_HUMAN | LOX | Lysyl oxidase | alpha-Glucosidase (alpha-Glu)
Type:
PROTEIN
Mol. Mass.:
46954.13
Organism:
Human
Description:
ChEMBL_306619
Residue:
417
Sequence:
MRFAWTVLLLGPLQLCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSLGSQYQPQRRRDPGAAVPGAANASAQQPRTPILLIRDNRTAAARTRTAGSSGVTAGRPRPTARHWFQAGYSTSRAREAGASRAENQTAPGEVPALSNLRPPSRVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPRPGGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYGYHRRFACTAHTQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGCTISPY
  
Inhibitor
Name:
BDBM50463620
Synonyms:
CHEMBL4240937
Type:
Small organic molecule
Emp. Form.:
C26H22N4O
Mol. Mass.:
406.49
SMILES:
CCN1\C(C=Cc2ccccc12)=C1/C(=O)N(N=C1Nc1ccccc1)c1ccccc1 |c:4,18|
Structure:
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