Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50465049
Substrate
n/a
Meas. Tech.
ChEMBL_1783752 (CHEMBL4255269)
Ki
1350±n/a nM
Citation
 Cooper, AG; MacDonald, C; Glass, M; Hook, S; Tyndall, JDA; Vernall, AJ Alkyl indole-based cannabinoid type 2 receptor tools: Exploration of linker and fluorophore attachment. Eur J Med Chem 145:770-789 (2018) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50465049
Synonyms:
CHEMBL4287330
Type:
Small organic molecule
Emp. Form.:
C25H29NO4
Mol. Mass.:
407.5021
SMILES:
CCCOc1ccc2n(CC3CCOCC3)cc(C(=O)c3ccc(OC)cc3)c2c1
Structure:
Search PDB for entries with ligand similarity: