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Target
Thromboxane-A synthase
Ligand
BDBM7882
Substrate
n/a
Meas. Tech.
ChEBML_210097
IC50
670000±n/a nM
Citation
 Cross, PE; Dickinson, RP; Parry, MJ; Randall, MJ Selective thromboxane synthetase inhibitors. 1. 1-[(Aryloxy)alkyl]-1H-imidazoles. J Med Chem 28:1427-32 (1985) [PubMed]  Article 
Target
Name:
Thromboxane-A synthase
Synonyms:
Thromboxane Alpha | Thromboxane synthase | Thromboxane-A synthase | TXA synthase | Thromboxane A2 Synthase | P450 TxA2 | Thromboxane prostanoid | Cytochrome P450 5A1 | TXS | THAS_HUMAN | TBXAS1 | CYP5 | CYP5A1 | TXAS | Thromboxane A2 Synthase (P450 TxA2)
Type:
Enzyme
Mol. Mass.:
60524.67
Organism:
Human
Description:
P24557
Residue:
533
Sequence:
MEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR
  
Inhibitor
Name:
BDBM7882
Synonyms:
CHEMBL540 | 1H-imidazole | imidazole | Imidazole (Im) | US9138393, Imidazole | US9144538, Imidazole
Type:
Small organic molecule
Emp. Form.:
C3H4N2
Mol. Mass.:
68.04
SMILES:
c1c[nH]cn1
Structure:
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