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Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM50017452
Substrate
n/a
Meas. Tech.
ChEMBL_201213 (CHEMBL804009)
Ki
6000±n/a nM
Citation
 Huff, JR; King, SW; Saari, WS; Springer, JP; Martin, GE; Williams, M Bioactive conformation of 1-arylpiperazines at central serotonin receptors. J Med Chem 28:945-8 (1985) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT-1B | 5-HT1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | 5ht1b | Htr1b | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1B
Type:
Protein
Mol. Mass.:
43173.33
Organism:
Rattus norvegicus (Rat)
Description:
P28564
Residue:
386
Sequence:
MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG
  
Inhibitor
Name:
BDBM50017452
Synonyms:
2-chloro-6-piperazin-1-ylpyrazine | 6'-Chloro-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl | 6'-Chloro-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl(MK-212) | CHEMBL269521 | L-630,571 | MK 212 | MK-212
Type:
Small organic molecule
Emp. Form.:
C8H11ClN4
Mol. Mass.:
198.653
SMILES:
Clc1cncc(n1)N1CCNCC1
Structure:
Search PDB for entries with ligand similarity: